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UM research team develops novel glycan-based strategy to treat intervertebral disc degeneration

UM develops GMOC into a polysaccharide glue that can ‘outsmart’ enzyme degradation and remain intact in the intervertebral disc tissue to combat tissue degeneration

With the global population ageing, intervertebral disc degeneration (IDD) has become a leading cause of lower back pain among modern populations, yet effective treatment options remain limited. A research team led by Wang Chunming, professor in the Institute of Chinese Medical Sciences (ICMS) at the University of Macau (UM), has developed a ‘glue’ derived from glucomannan that is designed to repair damaged intervertebral disc tissue, offering a promising new approach to alleviating IDD. The research has been published in the international journal Nature Communications.


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